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This paper details the proceedings, outputs and action plan points from the Regional Workshop on Laboratory Quality and Bio-Safety (RWLQB), 2018. The workshop aimed to provide an opportunity for knowledge sharing and coworking between members of the Greater Mekong Subregion (GMS) Health Security Project (HS). The workshop was attended by delegates and health care directors representing Cambodia, Lao PDR, and Myanmar, alongside representatives from healthcare and development bodies including ADB, WHO, IPC, USCDC, and OIE attended the event at Angkor Paradise in Siem Reap, Cambodia, from 14th – 15th August 2018. Download